We introduce two generalizations, the first of which generalizes the concept of multiresolution analysis. We define the irregular generalized multiresolution analysis (IGMRA). This structure is defined taking translations on sets that are not necessarily regular lattices, for which certain density requirements are required, and without using dilations, also allows each subspace of IGMRA to be generated by outer frames of translations of different functions. The second generalization concerns the concept of association of wavelets to these new structures. We take frames of translations of a countable set of functions, which we called *generalized wavelets*, and define the concept of association of these generalized wavelets to those previously defined IGMRA. In the next stage, we prove two existence theorems. In the first theorem, we prove existence of IGMRA, and in the second existence of generalized wavelets associated with it. In the latter, we show that we are able to associate frames of translations with optimal localization properties, to IGMRA. In the last section of this paper, concrete examples of these structures are presented for
and for
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